Considering the membrane fouling problem in submerged anaerobic membrane bioreactors, a set of submerged double-shaft rotary anaerobic membrane bioreactor (SDRAnMBR) was constructed by applying a double-shaft rotary module to submerged anaerobic bioreactor, and the theoretic analysis of the characteristics of hydraulics dynamics in SDRAnMBR has been performed. The membrane fouling performance for treatment of synthetic brewery wastewater was investigated by SDRAnMBR. The results of a theoretical analysis showed that the effects of homogenization, interleaving oscillation and three-phase rotating flow were produced within SDRAnMBR. Owing to their synergistic effect, the characteristics of shear, turbulence, oscillation and mass transfer within rotating fluid were enhanced so that the concentration polarization was reduced and permeate flux increased. The experiment results showed that SDRAnMBR had good anti-contamination performance and could maximize the reduction and control of the membrane fouling, proving the theoretic analysis on the characteristics of hydraulics dynamics in SDRAnMBR.